Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186174 | 0.98 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2HSD17B10RECQLFKBP1A | |
| SCHEMBL154453 | 0.98 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2HSD17B10RECQLFKBP1A | |
| SCHEMBL185522 | 0.98 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2HSD17B10RECQLFKBP1A | |
| SCHEMBL18555206 | 0.90 | HSD17B10 (0.51) | SMN1; SMN2USP2HSD17B10RECQLKLK7 | |
| SCHEMBL31148667 | 0.90 | HSD17B10 (0.51) | SMN1; SMN2USP2HSD17B10RECQLKLK7 | |
| SCHEMBL18555204 | 0.90 | HSD17B10 (0.51) | SMN1; SMN2USP2HSD17B10RECQLKLK7 | |
| SCHEMBL13804186 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2HSD17B10RECQLCA12 | |
| SCHEMBL15116754 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2HSD17B10RECQLCA12 | |
| SCHEMBL16604806 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2HSD17B10RECQLCA12 | |
| SCHEMBL16359137 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2HSD17B10RECQLCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117213-A | Heteroaryl compound and synthesis thereof and purification process | 西格诺药品有限公司 | 2016-11-16 | — | — | CN | disclosed |