Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.38 |
| ▸ | FDPS | P14324 | 9/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28792359 | 1.00 | TSHR (0.42) | TSHRTHRBGGPS1FDPSDNM1 | |
| SCHEMBL11669918 | 1.00 | TSHR (0.42) | TSHRTHRBGGPS1FDPSDNM1 | |
| SCHEMBL28062516 | 1.00 | TSHR (0.42) | TSHRTHRBGGPS1FDPSDNM1 | |
| SCHEMBL9858335 | 0.97 | TSHR (0.37) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL56177 | 0.89 | — | — | |
| SCHEMBL11814630 | 0.79 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL56626 | 0.77 | — | — | |
| SCHEMBL23790491 | 0.77 | GGPS1 (0.41) | TSHRTHRBGGPS1FDPSDNM1 | |
| SCHEMBL6182237 | 0.77 | TSHR (0.40) | TSHRTHRBGGPS1FDPSDNM1 | |
| SCHEMBL2573738 | 0.77 | TSHR (0.44) | TSHRTHRBGGPS1FDPSCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732613-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-11-30 | — | — | CN | disclosed |