Metaxon

Metaxon

SCHEMBL28111499

Cc1cc(Cl)ccc1OCC(=O)O.O=C(O)CCOc1ccccc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 6/20 0.67
PPARG P37231 3/20 0.67
NPSR1 Q6W5P4 1/20 0.59
PPARA Q07869 1/20 0.59
PTGDR2 Q9Y5Y4 3/20 0.53
TDP1 Q9NUW8 2/20 0.52
MCL1 Q07820 1/20 0.51
TSHR P16473 1/20 0.51
MAPT P10636 2/20 0.51
FFAR1 O14842 1/20 0.51
TP53 P04637 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
HIF1A Q16665 1/20 0.50
HTT P42858 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALOX15 P16050 1/20 0.50
ANO1 Q5XXA6 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mcpb SCHEMBL28161249 0.90 KDM4E (0.60) PPARDPPARGNPSR1TDP1MCL1
SCHEMBL3667070 0.85 KDM4E (0.65) NPSR1PTGDR2MCL1TSHRMAPT
Metaxon SCHEMBL117877 0.85 TDP1 (0.70) PPARDPPARGNPSR1PTGDR2TDP1
Mcpb SCHEMBL11654380 0.84 KDM4E (0.65) PPARDPPARGNPSR1TDP1TSHR
Metaxon SCHEMBL27799919 0.84 PTGDR2 (0.66) PPARDPPARGNPSR1PTGDR2TDP1
SCHEMBL11739981 0.84 KDM4E (0.63) NPSR1PTGDR2MCL1TSHRMAPT
Metaxon SCHEMBL28800416 0.84 TDP1 (0.68) PPARDPPARGNPSR1PTGDR2TDP1
Metaxon SCHEMBL27616565 0.84 TDP1 (0.68) PPARDPPARGNPSR1PTGDR2TDP1
Metaxon SCHEMBL3533162 0.84 TDP1 (0.68) PPARDPPARGNPSR1PTGDR2TDP1
Metaxon SCHEMBL27765431 0.84 TDP1 (0.68) PPARDPPARGNPSR1PTGDR2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103561564-B Stacked herbicide tolerance event 8264.44.06.1, related transgenic soybean lines, and detection thereof 陶氏益农公司 2016-11-16 CN disclosed