Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.67 |
| ▸ | ALDH2 | P05091 | 9/20 | 0.59 |
| ▸ | MAOA | P21397 | 5/20 | 0.59 |
| ▸ | MAOB | P27338 | 5/20 | 0.59 |
| ▸ | TERT | O14746 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | XDH | P47989 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2109464 | 0.89 | ALDH2 (0.76) | ALDH2MAOAMAOB | |
| SCHEMBL950959 | 0.88 | MAPT (0.72) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL12946416 | 0.87 | HRH3 (0.78) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL31241609 | 0.84 | ALDH2 (0.79) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL2107434 | 0.84 | ALDH2 (0.77) | ALDH2MAOAMAOB | |
| SCHEMBL31241612 | 0.84 | ALDH2 (0.80) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL11556173 | 0.83 | ALDH2 (0.73) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL740753 | 0.83 | ALDH2 (0.80) | HRH3ALDH2MAOAMAOB | |
| SCHEMBL30527918 | 0.82 | ALDH2 (0.80) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8983891 | 0.82 | MAPT (0.68) | ALDH1A1MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146450-B | Formoononetin derivative, preparation method and medical usage | 南京华迈生物医药科技有限公司 | 2019-02-15 | — | — | CN | disclosed |
| CN-106146450-A | Formoononetin derivant, its preparation method and medical usage | 南京华迈生物医药科技有限公司 | 2016-11-23 | — | — | CN | disclosed |