Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16765459 | 0.89 | JAK3 (0.82) | JAK3 | |
| SCHEMBL16765010 | 0.88 | JAK3 (0.73) | JAK3 | |
| SCHEMBL16765009 | 0.88 | JAK3 (0.73) | JAK3 | |
| SCHEMBL16765153 | 0.86 | JAK3 (1.00) | JAK3 | |
| SCHEMBL20125403 | 0.86 | JAK3 (1.00) | JAK3 | |
| SCHEMBL28111558 | 0.80 | JAK3 (0.66) | JAK3 | |
| SCHEMBL16764862 | 0.79 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16764861 | 0.79 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16764910 | 0.79 | JAK3 (0.83) | JAK3 | |
| SCHEMBL16764911 | 0.79 | JAK3 (0.83) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061973-B | Pyrrolo [2,3-D ] pyrimidinyl, pyrrolo [2,3-B ] pyrazinyl and pyrrolo [2,3-D ] pyridylacrylamide | 辉瑞公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-106061973-A | Pyrrolo [2,3-D ] pyrimidinyl, pyrrolo [2,3-B ] pyrazinyl and pyrrolo [2,3-D ] pyridylacrylamide | 辉瑞公司 | 2016-10-26 | — | — | CN | disclosed |