Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 14/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 5/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111171 | 0.90 | KLKB1 (0.61) | KLKB1CARM1 | |
| SCHEMBL28836607 | 0.88 | KLKB1 (0.61) | KLKB1CARM1F2F10PRSS1 | |
| SCHEMBL28534581 | 0.87 | CARM1 (0.66) | KLKB1CARM1 | |
| SCHEMBL28111097 | 0.87 | KLKB1 (0.59) | KLKB1CARM1 | |
| SCHEMBL18604957 | 0.86 | KLKB1 (0.66) | KLKB1CARM1 | |
| SCHEMBL18604895 | 0.86 | KLKB1 (0.78) | KLKB1CARM1F2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL18604877 | 0.85 | KLKB1 (0.77) | KLKB1CARM1F2F10PRSS1 | |
| SCHEMBL29245768 | 0.84 | KLKB1 (0.62) | KLKB1CARM1F2F10PRSS1 | |
| SCHEMBL25261667 | 0.83 | KLKB1 (0.60) | KLKB1CARM1F2F10PRSS1 | |
| SCHEMBL28111227 | 0.82 | KLKB1 (0.58) | KLKB1CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106257976-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2016-12-28 | — | — | CN | disclosed |