Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | F2 | P00734 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833634 | 0.84 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8117886 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL9133608 | 0.81 | MAPT (0.83) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL31682859 | 0.80 | KDM4E (0.73) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL16896204 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL20769964 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL2807131 | 0.77 | KDM4E (0.65) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL2348593 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6257352 | 0.76 | MAPT (0.82) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL16896172 | 0.76 | KDM4E (0.76) | KDM4EALDH1A1HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103453-A | It is condensed 5 oxazolidinone derivatives | 大日本住友制药株式会社 | 2016-11-09 | — | — | CN | disclosed |