Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD74 | P04233 | 3/20 | 0.52 |
| ▸ | MIF | P14174 | 3/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138490 | 0.75 | MTOR (0.58) | CD74MIFMTORCMA1MEN1 | |
| SCHEMBL29522354 | 0.75 | MTOR (0.58) | CD74MIFMTORCMA1MEN1 | |
| SCHEMBL25055361 | 0.69 | CD74 (1.00) | CD74MIFMTORMEN1KMT2A | |
| SCHEMBL29522322 | 0.65 | MTOR (0.58) | CD74MIFMTORMEN1KMT2A | |
| SCHEMBL136928 | 0.65 | MTOR (0.58) | CD74MIFMTORMEN1KMT2A | |
| SCHEMBL20017654 | 0.65 | MTOR (0.47) | MTORCMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL8115518 | 0.65 | CMA1 (0.79) | CMA1MEN1KMT2ATP53L3MBTL1 | |
| SCHEMBL16182645 | 0.65 | CD74 (0.44) | CD74MIFMTORCMA1MEN1 | |
| SCHEMBL9056105 | 0.64 | CD74 (0.53) | CD74MIFCMA1MEN1KMT2A | |
| SCHEMBL6394855 | 0.64 | CMA1 (0.58) | CD74MIFCMA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117213-A | Heteroaryl compound and synthesis thereof and purification process | 西格诺药品有限公司 | 2016-11-16 | — | — | CN | claimed |