Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173847 | 0.89 | NAMPT (0.84) | NAMPTCYP2C9 | |
| SCHEMBL22402282 | 0.88 | NAMPT (0.86) | NAMPTCYP2C9 | |
| SCHEMBL165510 | 0.88 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL174646 | 0.87 | NAMPT (0.82) | NAMPTCYP2C9 | |
| SCHEMBL174475 | 0.87 | NAMPT (0.84) | NAMPTCYP2C9 | |
| SCHEMBL176173 | 0.87 | NAMPT (0.84) | NAMPTCYP2C9 | |
| SCHEMBL28162252 | 0.86 | NAMPT (0.83) | NAMPTCYP2C9 | |
| SCHEMBL175668 | 0.86 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL29635653 | 0.86 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL21132371 | 0.86 | NAMPT (0.79) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103270023-B | 4- { [ (pyridin-3-yl-methyl) aminocarbonyl ] amino } benzene-sulfone derivatives as NAMPT inhibitors for the treatment of diseases such as cancer | 福马TM有限责任公司 | 2016-11-02 | — | — | CN | claimed |