Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430324 | 0.92 | MGAM (0.59) | MGAMMAOBNPC1RAB9ACHRNB2 | |
| Hydrochloric Acid SCHEMBL27688595 | 0.91 | MGAM (0.58) | MGAMMAOBNPC1RAB9ACHRNB2 | |
| SCHEMBL27920825 | 0.91 | MGAM (0.58) | MGAMMAOBNPC1RAB9ACHRNB2 | |
| Hydrochloric Acid SCHEMBL27707542 | 0.91 | MGAM (0.58) | MGAMMAOBNPC1RAB9ACHRNB2 | |
| SCHEMBL30546532 | 0.81 | MAOB (0.56) | MAOBNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL21945258 | 0.81 | MAOB (0.53) | MAOBNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1017525 | 0.81 | MAOB (0.56) | MAOBNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL31058620 | 0.81 | MGAM (0.56) | MGAMMAOBRAB9ACHRNB2CHRNA7 | |
| SCHEMBL27427053 | 0.81 | MGAM (0.56) | MGAMMAOBRAB9ACHRNB2CHRNA7 | |
| Hydrochloric Acid SCHEMBL27744672 | 0.81 | MGAM (0.52) | MGAMMAOBNPC1RAB9ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103906735-B | Novel aryl-quinoline derivatives | 霍夫曼-拉罗奇有限公司 | 2016-12-07 | — | — | CN | disclosed |