SCHEMBL28113

SCHEMBL28113

[NH]CC1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27809 0.84
SCHEMBL26653 0.84
SCHEMBL5188156 0.83 ESR1 (0.38)
SCHEMBL752827 0.83
SCHEMBL1917422 0.83 PLG (0.44)
SCHEMBL749703 0.83
SCHEMBL8598333 0.76 LIPA (0.42)
SCHEMBL1096831 0.75
SCHEMBL2375099 0.74 PLG (0.60)
SCHEMBL129349 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1769 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4395897-A1 NOVEL RAS INHIBITORS KHR Biotec GmbH (DE) 2024-07-10 EP claimed
CN-118234715-A Novel RAS inhibitors KHR生物技术有限公司 2024-06-21 CN claimed
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-06-20 US claimed
US-20240124474-A1 HER2 MUTATION INHIBITORS ARRAY BIOPHARMA INC. (US) 2024-04-18 US claimed
WO-2024056619-A1 1H-CYCLOPENTA[B]BENZOFURAN DERIVATIVES FOR THE PREVENTION AND TREATMENT OF VIRUS DISEASES KHR Biotec GmbH (DE) 2024-03-21 WO claimed
EP-4313943-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-02-07 EP claimed
CN-117043140-A Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances 拜耳公司 2023-11-10 CN claimed
WO-2023151636-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BEIGENE , LTD. (KY) 2023-08-17 WO claimed
CN-116239523-A Pyridylpiperazine compound and preparation method and application thereof 浙江工业大学 2023-06-09 CN claimed
CN-116239524-A Arylpyridine compound and preparation method and application thereof 浙江工业大学 2023-06-09 CN claimed
WO-1997003056-A1 HERBICIDAL SULPHONYLAMINO(THIO)CARBONYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1997-01-30 WO claimed
WO-1996022982-A1 SULPHONYL AMINO(THIO)CARBONYL-1,2,4-TRIAZOLIN(THI)ONE DERIVATIVES, THE PRODUCTION THEREOF AND THE USE THEREOF AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-08-01 WO claimed
US-5492905-A NERVOUS SYSTEM DISORDERS ZENECA LIMITED (GB) 1996-02-20 US claimed
WO-1993003719-A1 ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY ABBOTT LABORATORIES (US) 1993-03-04 WO claimed
US-5183818-A Also for inhibiting leukotriene biosynthesis ABBOTT LABORATORIES (US) 1993-02-02 US claimed
EP-0421819-A1 Therapeutic nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1991-04-10 EP claimed
WO-1990008147-A1 PURINE NUCLEOSIDES, PROCESS FOR PRODUCING THEM, AND DRUGS CONTAINING THESE COMPOUNDS BOEHRINGER MANNHEIM GMBH (DE) 1990-07-26 WO claimed
EP-0191542-B1 ARYLCYCLOBUTYLALKYL AMINES AND THEIR USE AS ANTIDEPRESSIVE MEDICINES The Boots Company PLC (GB) 1988-06-08 EP claimed
EP-0191542-A1 Arylcyclobutylalkyl amines and their use as antidepressive medicines The Boots Company PLC (GB) 1986-08-20 EP claimed
US-4430269-A 12'-Iodo derivatives of dimeric indole-dihydroindole alkaloids, and process for preparing them ELI LILLY AND COMPANY (US) 1984-02-07 US claimed