Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 11/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.51 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4310530 | 0.85 | PIM1 (0.53) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL1701238 | 0.79 | PIM1 (0.56) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL28644005 | 0.77 | AKR1B1 (0.44) | KDM4ETSHRMAPTHPGDHSD17B10 | |
| SCHEMBL11739995 | 0.77 | PIM1 (0.57) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL22588087 | 0.76 | PIM1 (0.51) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL6333731 | 0.76 | AKR1B1 (0.53) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL22587735 | 0.72 | PIM1 (0.44) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL20563607 | 0.72 | PIM1 (0.56) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL29127652 | 0.72 | PIM1 (0.54) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL9424948 | 0.72 | PIM1 (0.55) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478564-B | Cathepsin K inhibitors and uses thereof | 广东东阳光药业有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-106478564-A | Cathepsin K inhibitor and application thereof | 广东东阳光药业有限公司 | 2017-03-08 | — | — | CN | disclosed |