Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.86 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL8845002 | 0.96 | TSHR (0.92) | TSHRALDH1A1TDP1THRBLMNA | |
| SCHEMBL9285670 | 0.96 | TSHR (0.92) | TSHRALDH1A1TDP1THRBLMNA | |
| SCHEMBL3164 | 0.96 | — | — | |
| SCHEMBL276808 | 0.96 | — | — | |
| Methylene Chloride SCHEMBL25428166 | 0.92 | — | — | |
| SCHEMBL4879054 | 0.92 | — | — | |
| Butyl Chloride SCHEMBL8040894 | 0.92 | TSHR (0.86) | TSHRALDH1A1TDP1THRBLMNA | |
| Fluoride SCHEMBL21873339 | 0.92 | — | — | |
| SCHEMBL22186971 | 0.92 | TSHR (1.00) | TSHRALDH1A1TDP1THRBLMNA | |
| SCHEMBL5575823 | 0.92 | TSHR (1.00) | TSHRALDH1A1TDP1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178198-A | Preparation method of cyflufenapyr | 南通泰禾化工股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-108503652-A | A kind of fully synthetic preparation method of chemistry of crotons alkane diterpene Prostratin | 西安交通大学 | 2018-09-07 | — | — | CN | disclosed |
| CN-107629005-A | Polysubstituted phenylpyrazole derivatives and its production and use | 王泊理 | 2018-01-26 | — | — | CN | disclosed |
| CN-105017061-B | A kind of synthetic method of ENBREL card life | 苏州富士莱医药股份有限公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-104211696-B | A kind of preparation method of TMC-435 important intermediate | HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-01-04 | — | — | CN | disclosed |