Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355731 | 0.91 | HDAC6 (1.00) | HDAC6KDM4EPOLBHSD17B2KMT2A | |
| SCHEMBL1354888 | 0.91 | HDAC6 (1.00) | HDAC6KDM4EPOLBHSD17B2KMT2A | |
| SCHEMBL1354864 | 0.91 | HDAC6 (1.00) | HDAC6KDM4EPOLBHSD17B2KMT2A | |
| SCHEMBL31550983 | 0.91 | HDAC6 (1.00) | HDAC6KDM4EPOLBHSD17B2KMT2A | |
| SCHEMBL3366969 | 0.91 | HDAC6 (1.00) | HDAC6KDM4EPOLBHSD17B2KMT2A | |
| SCHEMBL8887372 | 0.89 | KMT2A (0.72) | HDAC6KDM4EPOLBHSD17B2KMT2A | |
| SCHEMBL1354918 | 0.89 | HDAC6 (0.97) | HDAC6KDM4EPOLBHSD17B2KMT2A | |
| SCHEMBL30035251 | 0.87 | HDAC6 (0.59) | HDAC6KDM4EPOLBGAAPKM | |
| SCHEMBL28867985 | 0.87 | HDAC6 (0.59) | HDAC6KDM4EPOLBGAAPKM | |
| SCHEMBL1354950 | 0.86 | HDAC6 (0.91) | HDAC6KDM4EPOLBHSD17B2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232110-A | Ion channel activation agent and using method | 弗莱克斯制药股份有限公司 | 2016-12-14 | — | — | CN | disclosed |