SCHEMBL28114342

SCHEMBL28114342

CCOC(=O)c1ccc(-c2c3ccccc3c(-c3cccc4ccccc34)c3ccccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
CDC25B P30305 4/20 0.49
F2RL3 Q96RI0 1/20 0.47
TNKS O95271 1/20 0.47
CDC25A P30304 1/20 0.46
CDC25C P30307 1/20 0.46
EGFR P00533 1/20 0.46
KDR P35968 1/20 0.46
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45
RARA P10276 1/20 0.45
RARB P10826 1/20 0.45
RARG P13631 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
ESR1 P03372 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
ESR2 Q92731 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13247931 0.89 HDAC8 (0.56) KDM4ECDC25BF2RL3TNKSCDC25A
SCHEMBL6352575 0.87 KDM4E (0.59) KDM4EF2RL3TNKSRARARARB
SCHEMBL31426904 0.87 KDM4E (0.59) KDM4EF2RL3TNKSRARARARB
SCHEMBL21164596 0.83 TNKS (0.54) KDM4ECDC25BF2RL3TNKSEGFR
SCHEMBL21164767 0.82 TNKS (0.53) KDM4ECDC25BF2RL3TNKSEGFR
SCHEMBL13966910 0.79 TSHR (0.59) KDM4ECDC25BCDC25ACDC25CMEN1
SCHEMBL2129231 0.79 CDC25B (0.62) KDM4ECDC25BCDC25ACDC25CMEN1
SCHEMBL20494623 0.79 CDC25B (0.50) KDM4ECDC25BF2RL3TNKSCDC25A
SCHEMBL21164816 0.78 CDC25B (0.49) KDM4ECDC25BF2RL3TNKSCDC25A
SCHEMBL28004714 0.78 CDC25B (0.61) KDM4ECDC25BCDC25ACDC25CMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106316844-A Preparation method for 4-(9-(beta-naphthaline)-10-anthryl) ethyl benzoate 天津大学 2017-01-11 CN claimed
CN-106316844-A Preparation method for 4-(9-(beta-naphthaline)-10-anthryl) ethyl benzoate 天津大学 2017-01-11 CN disclosed
CN-106316844-A Preparation method for 4-(9-(beta-naphthaline)-10-anthryl) ethyl benzoate 天津大学 2017-01-11 CN disclosed
CN-106316844-A Preparation method for 4-(9-(beta-naphthaline)-10-anthryl) ethyl benzoate 天津大学 2017-01-11 CN disclosed