SCHEMBL28114437

SCHEMBL28114437

COCc1ccc(COC(=O)C2CC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.43
FABP5 Q01469 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 5/20 0.42
ATM Q13315 2/20 0.42
KDM4E B2RXH2 1/20 0.42
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11834516 0.91 GAA (0.46) FABP7FABP5MEN1KMT2AALDH1A1
SCHEMBL8191635 0.86 FABP7 (0.58) FABP7FABP5ALDH1A1HTTSMN1; SMN2
SCHEMBL8502974 0.86 FABP7 (0.58) FABP7FABP5ALDH1A1HTTSMN1; SMN2
SCHEMBL14937640 0.86 HPGD (0.52) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL24157307 0.83 KMT2A (0.58) MEN1KMT2AALDH1A1ATMHTT
SCHEMBL14937275 0.82 MEN1 (0.56) MEN1KMT2AALDH1A1ATMTSHR
SCHEMBL28288204 0.82 MEN1 (0.43) FABP7FABP5MEN1KMT2AALDH1A1
SCHEMBL28841067 0.82 FABP7 (0.56) FABP7FABP5MEN1KMT2AALDH1A1
SCHEMBL28520882 0.82 FABP7 (0.56) FABP7FABP5MEN1KMT2AALDH1A1
SCHEMBL10917021 0.81 FABP7 (0.58) FABP7FABP5KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106323212-A ZIGBEE-based synchronous swivel bridge three-coordinate safe-displacement real-time monitoring system and working method thereof 江苏建筑职业技术学院 2017-01-11 CN claimed
CN-106323212-A ZIGBEE-based synchronous swivel bridge three-coordinate safe-displacement real-time monitoring system and working method thereof 江苏建筑职业技术学院 2017-01-11 CN disclosed