SCHEMBL28114735

SCHEMBL28114735

c1ccc(CN2CCC(NC3CC3c3ccccc3)CC2)cc1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 20/20 0.77
MAOB P27338 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16987783 0.91 KDM1A (0.73) KDM1A
SCHEMBL16987781 0.91 KDM1A (0.73) KDM1A
SCHEMBL18817780 0.89 KDM1A (0.70) KDM1A
SCHEMBL18817778 0.89 KDM1A (0.70) KDM1A
SCHEMBL18817783 0.89 KDM1A (0.70) KDM1A
SCHEMBL18817781 0.89 KDM1A (0.70) KDM1A
SCHEMBL16987680 0.88 KDM1A (1.00) KDM1AMAOB
SCHEMBL16987682 0.88 KDM1A (1.00) KDM1AMAOB
SCHEMBL18817773 0.86 KDM1A (0.72) KDM1A
SCHEMBL20308859 0.86 KDM1A (0.63) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106164066-A Cyclopropylamines as lsd1 inhibitors 因赛特公司 2016-11-23 CN claimed
CN-106164066-A Cyclopropylamines as lsd1 inhibitors 因赛特公司 2016-11-23 CN disclosed