Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL193700 | 0.90 | — | — | |
| Monoethanolamine SCHEMBL28876126 | 0.87 | — | — | |
| Benzene SCHEMBL28307809 | 0.87 | GLRA1 (0.33) | TSHRGLRA1SLC6A9OR51E2 | |
| Monoethanolamine SCHEMBL4305455 | 0.87 | — | — | |
| Benzene SCHEMBL1227479 | 0.83 | TSHR (0.73) | ALDH1A1TSHRGLRA1SLC6A9OR51E2 | |
| Benzene SCHEMBL28184177 | 0.79 | TSHR (0.67) | ALDH1A1TSHR | |
| Benzene SCHEMBL27952644 | 0.79 | TSHR (0.67) | ALDH1A1TSHR | |
| Benzene SCHEMBL27937396 | 0.79 | TSHR (0.67) | ALDH1A1TSHR | |
| Benzene SCHEMBL29175842 | 0.79 | TSHR (0.67) | ALDH1A1TSHR | |
| Benzene SCHEMBL27326261 | 0.79 | TSHR (0.67) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103088328-B | A kind of galvanized steel sheet surface silane finish and preparation method thereof | 芜湖恒坤汽车部件有限公司 | 2016-12-28 | — | — | CN | claimed |
| CN-108034949-B | A kind of environment protection water-based gas phase long-acting antirust liquid composition and preparation and application | 辽宁宝瑞科技有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-108034949-A | A kind of environment protection water-based gas phase long-acting antirust liquid composition and preparation and application | 辽宁宝瑞科技有限公司 | 2018-05-15 | — | — | CN | disclosed |
| CN-106220921-A | A kind of brake ribbon based on modified composite fiber and preparation method thereof | 竹洪燕 | 2016-12-14 | — | — | CN | disclosed |