Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16044470 | 0.81 | TDP1 (0.53) | KMT2ATDP1L3MBTL1POLBGPR35 | |
| SCHEMBL30514277 | 0.81 | KMT2A (0.53) | KMT2AHTTTDP1L3MBTL1POLB | |
| SCHEMBL8569018 | 0.80 | TDP1 (0.58) | KMT2ATDP1POLBCES2CES1 | |
| SCHEMBL17819747 | 0.80 | TDP1 (0.64) | KMT2AHTTTDP1L3MBTL1POLB | |
| SCHEMBL355378 | 0.80 | TDP1 (0.64) | KMT2AHTTTDP1L3MBTL1POLB | |
| SCHEMBL5098760 | 0.79 | TSHR (0.59) | KMT2AHTTTDP1L3MBTL1POLB | |
| SCHEMBL25176225 | 0.78 | TDP1 (0.53) | KMT2ATDP1L3MBTL1GPR35TSHR | |
| SCHEMBL793112 | 0.78 | TDP1 (0.49) | KMT2ATDP1L3MBTL1GPR35TSHR | |
| SCHEMBL16108925 | 0.78 | TDP1 (0.49) | KMT2ATDP1L3MBTL1POLBGPR35 | |
| SCHEMBL28103813 | 0.78 | TDP1 (0.43) | KMT2AHTTTDP1L3MBTL1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187803-A | The synthetic method of the amides compound that a kind of phosphorus oxychloride promotes | 中国人民解放军63975部队 | 2016-12-07 | — | — | CN | disclosed |