SCHEMBL28115066

SCHEMBL28115066

Cc1ccc(C)c2c1C(=O)c1cccc(Cl)c1C2=O

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.49
CYP1A1 P04798 1/20 0.49
CYP1A2 P05177 1/20 0.49
NPC1 O15118 1/20 0.49
ALDH1A1 P00352 1/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
CASP3 P42574 1/20 0.49
RAB9A P51151 1/20 0.49
HBB P68871 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ADORA2A P29274 2/20 0.46
ELANE P08246 2/20 0.45
CTSG P08311 1/20 0.45
AR P10275 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12105727 0.90 CYP1A1 (0.50) NSD2CYP1A1CYP1A2NPC1ALDH1A1
SCHEMBL125609 0.85 NSD2 (0.55) NSD2ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL1476410 0.84 ADORA2A (0.57) NSD2CYP1A1CYP1A2ALDH1A1TSHR
SCHEMBL122441 0.83 NSD2 (0.62) NSD2ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL2767533 0.82 ADORA2A (0.67) NSD2CYP1A1CYP1A2NPC1ALDH1A1
SCHEMBL4585020 0.81 NSD2 (0.55) NSD2ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL11024502 0.81 ADORA2A (0.70) NSD2CYP1A1CYP1A2NPC1ALDH1A1
SCHEMBL23271726 0.80 NSD2 (0.47) NSD2CYP1A1CYP1A2ADORA2AAR
SCHEMBL30003414 0.80 NSD2 (0.47) NSD2CYP1A1CYP1A2ADORA2AAR
Anthraquinone SCHEMBL5172785 0.79 ADORA2A (0.57) NSD2ALDH1A1CYP3A4MAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106349294-A Aniline anthraquinone late transition metal compound and preparation method and application thereof 东华大学 2017-01-25 CN claimed
CN-106349294-A Aniline anthraquinone late transition metal compound and preparation method and application thereof 东华大学 2017-01-25 CN disclosed