SCHEMBL28115084

SCHEMBL28115084

CCCCOC(=O)C(C)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
GAA P10253 2/20 0.42
XBP1 P17861 1/20 0.42
ATM Q13315 1/20 0.42
NR5A2 O00482 1/20 0.42
NR5A1 Q13285 1/20 0.42
CNR2 P34972 3/20 0.41
LMNA P02545 1/20 0.40
RECQL P46063 1/20 0.40
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
AKR1C4 P17516 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28781425 0.96 ESR1 (0.43) ESR1L3MBTL1NPSR1GAAXBP1
SCHEMBL284356 0.94 ESR1 (0.46) ESR1NR5A2NR5A1LMNAALDH1A1
SCHEMBL284085 0.94 ESR1 (0.46) ESR1NR5A2NR5A1LMNAALDH1A1
SCHEMBL436935 0.94 ESR1 (0.46) ESR1NR5A2NR5A1LMNAALDH1A1
SCHEMBL283874 0.94 ESR1 (0.46) ESR1NR5A2NR5A1LMNAALDH1A1
SCHEMBL25273215 0.94 ESR1 (0.46) ESR1NR5A2NR5A1LMNAALDH1A1
SCHEMBL283852 0.94 ESR1 (0.46) ESR1NR5A2NR5A1LMNAALDH1A1
SCHEMBL20942816 0.94 ESR1 (0.46) ESR1NR5A2NR5A1LMNAALDH1A1
SCHEMBL22229452 0.94 ESR1 (0.46) ESR1NR5A2NR5A1LMNAALDH1A1
SCHEMBL11801616 0.94 ESR1 (0.46) ESR1NR5A2NR5A1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106517049-B 360 ° of large parts turnover devices of one kind and its working method 江苏建筑职业技术学院 2018-07-20 CN claimed
CN-106517049-A 360-degree large part turnover device and working method thereof 江苏建筑职业技术学院 2017-03-22 CN claimed
CN-106249620-A A kind of drilling device based on eM Plant analogue system and method for work thereof 徐州工程学院 2016-12-21 CN claimed
CN-108929396-A A kind of rare-earth metal catalyst system and the method for preparing high-cis conjugated diene polymer 北京化工大学 2018-12-04 CN disclosed
CN-106517049-A 360-degree large part turnover device and working method thereof 江苏建筑职业技术学院 2017-03-22 CN disclosed
CN-106249620-A A kind of drilling device based on eM Plant analogue system and method for work thereof 徐州工程学院 2016-12-21 CN disclosed