SCHEMBL28115115

SCHEMBL28115115

O=C(Cl)C(=O)OC1CCC1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.39
GPR35 Q9HC97 4/20 0.38
SERPINE1 P05121 1/20 0.36
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
NAAA Q02083 2/20 0.34
CYP2C19 P33261 1/20 0.34
MMP1 P03956 2/20 0.34
MMP9 P14780 2/20 0.34
MMP12 P39900 2/20 0.34
MMP2 P08253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
HTT P42858 1/20 0.32
CYP19A1 P11511 2/20 0.32
PARP10 Q53GL7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753333 0.93 EPHX1 (0.47) EPHX1GPR35CA12CA1CA2
SCHEMBL7603488 0.93 EPHX1 (0.47) EPHX1GPR35CA12CA1CA2
SCHEMBL28970081 0.90
Acetic Acid SCHEMBL27309321 0.87 EPHX1 (0.40) EPHX1GPR35CA12CA1CA2
SCHEMBL6623051 0.81 EPHX1 (0.48) EPHX1GPR35SERPINE1CA12CA1
SCHEMBL393224 0.79
SCHEMBL7418958 0.79 EPHX1 (0.41) EPHX1GPR35SERPINE1CA12CA1
SCHEMBL11591531 0.78 EPHX1 (0.50) EPHX1GPR35CA12CA1CA2
SCHEMBL28323024 0.77 EPHX1 (0.40) EPHX1GPR35SERPINE1CA12CA1
SCHEMBL4673299 0.77 EPHX1 (0.42) EPHX1GPR35SERPINE1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106457160-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2019-10-08 CN disclosed
CN-105873665-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2019-01-01 CN disclosed
CN-106457160-A Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2017-02-22 CN disclosed
CN-106232214-A Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2016-12-14 CN disclosed