Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL27551620 | 0.85 | TDP1 (0.36) | ALDH1A1CA2MAPK1CHRM1AKR1A1 | |
| SCHEMBL157028 | 0.85 | — | — | |
| SCHEMBL767045 | 0.83 | TDP1 (0.38) | ALDH1A1CA2MAPK1CHRM1AKR1A1 | |
| SCHEMBL11256020 | 0.83 | TDP1 (0.38) | ALDH1A1CA2MAPK1CHRM1AKR1A1 | |
| Acetic Acid SCHEMBL8992516 | 0.83 | FFAR3 (0.41) | ALDH1A1CA2MAPK1CHRM1AKR1A1 | |
| SCHEMBL230830 | 0.83 | TDP1 (0.38) | ALDH1A1CA2MAPK1CHRM1AKR1A1 | |
| SCHEMBL21219177 | 0.83 | TDP1 (0.38) | ALDH1A1CA2MAPK1CHRM1AKR1A1 | |
| SCHEMBL21225948 | 0.83 | TDP1 (0.38) | ALDH1A1CA2MAPK1CHRM1AKR1A1 | |
| SCHEMBL21519882 | 0.83 | TDP1 (0.38) | ALDH1A1CA2MAPK1CHRM1AKR1A1 | |
| SCHEMBL1262653 | 0.83 | TDP1 (0.38) | ALDH1A1CA2MAPK1CHRM1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749135-B | Substituted benzofuran formyl hydrazone analog derivative and preparation method thereof | 浙江大学 | 2019-07-19 | — | — | CN | claimed |
| CN-109354584-A | The method of one pot process 2- (4- hydroxy phenyl) -4- methyl-1,3-thiazole-5-carboxylic acid ethyl ester | 湖北理工学院 | 2019-02-19 | — | — | CN | claimed |
| CN-106279082-B | Substituted furans chalcone derivative and preparation method thereof | 浙江大学 | 2019-02-01 | — | — | CN | claimed |
| CN-106905340-B | Benzofuran fluoro flavanone derivative and preparation method thereof | 浙江大学 | 2019-02-01 | — | — | CN | claimed |
| CN-106279083-B | A kind of furocoumarin analog derivative and preparation method thereof | 浙江大学 | 2019-01-08 | — | — | CN | claimed |
| CN-108570017-A | The synthesis of 2- amino-4-methylthiazole-5-carboxylates | 西安格瑞德化工新材料有限公司 | 2018-09-25 | — | — | CN | claimed |
| CN-106243126-B | Substituted furans isoquinolines analog derivative and preparation method thereof | 浙江大学 | 2018-09-18 | — | — | CN | claimed |
| CN-106243121-B | Substituted furan-flavone alcohol derivatives and preparation method thereof | 浙江大学 | 2018-07-13 | — | — | CN | claimed |
| CN-106336417-B | Substituted furans isoflavonoid derivatives and preparation method thereof | 浙江大学 | 2018-07-13 | — | — | CN | claimed |
| CN-108218702-A | The preparation method of 2- acetyl fluoride ethyl acetate | 湖北卓熙氟化股份有限公司 | 2018-06-29 | — | — | CN | claimed |
| CN-106905340-A | Benzofuran fluoro flavanone derivative and preparation method thereof | 浙江大学 | 2017-06-30 | — | — | CN | claimed |
| CN-106749135-A | Substituted benzofuran formyl hydrazone analog derivative and preparation method thereof | 浙江大学 | 2017-05-31 | — | — | CN | claimed |
| CN-106336417-A | Substituted furan isoflavone derivative and preparation method thereof | 浙江大学 | 2017-01-18 | — | — | CN | claimed |
| CN-106336416-A | Furan flavone derivative and preparation method thereof | 浙江大学 | 2017-01-18 | — | — | CN | claimed |
| CN-110423228-A | A method of preparing darunavir intermediate | CHENGDU PORTON PHARMACY CO LTD | 2019-11-08 | — | — | CN | disclosed |
| CN-107043385-B | Method for preparing darunavir intermediate | 成都博腾药业有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-109956886-A | (Z)-[(4- methoxyphenyl) hydrazono-] preparation method of ethyl chloroacetate | 连云港恒运药业有限公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-106459037-A | Enantiomers of the n-(2-amino-5-fluoro-2-methylpentyl)-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridine-3-carboxamide, as well as of the di- and trifluoro derivatives for the treatment of cardiovascular diseases | 拜耳医药股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106414440-A | Aryl and heteroaryl substituted imidazo [1,2-a ] pyridine-3-carboxamides and their use | 拜耳制药股份公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-106336417-A | Substituted furan isoflavone derivative and preparation method thereof | 浙江大学 | 2017-01-18 | — | — | CN | disclosed |