SCHEMBL28116400

SCHEMBL28116400

N#CC1=C(C#N)C(=O)C(F)=CC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4507554 0.74
SCHEMBL27263084 0.74 PTPRC (0.35)
SCHEMBL27804071 0.73
SCHEMBL29243180 0.73 NSD2 (0.34)
Fluoride SCHEMBL27989004 0.73
SCHEMBL28222813 0.70
SCHEMBL28087315 0.69
SCHEMBL615573 0.68 MEN1 (0.31)
SCHEMBL29005930 0.67
SCHEMBL1393186 0.66 KDM4E (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106146710-B Cationic polymerization method 中国石油化工股份有限公司 2018-12-28 CN disclosed
CN-106317349-B Styrene-isomonoolefin-styrene triblock copolymer and preparation method thereof 中国石油化工股份有限公司 2018-11-02 CN disclosed
CN-106146703-B Cationic polymerization method 中国石油化工股份有限公司 2018-10-16 CN disclosed
CN-106146698-B Preparation method of halogenated polymer 中国石油化工股份有限公司 2018-10-16 CN disclosed
CN-106146696-B Cationic polymerization method 中国石油化工股份有限公司 2018-10-16 CN disclosed
CN-106146707-B Preparation method of halogenated polymer 中国石油化工股份有限公司 2018-09-21 CN disclosed
CN-106146697-B Cationic polymerization method 中国石油化工股份有限公司 2018-09-21 CN disclosed
CN-106146701-B Preparation method of halogenated polymer 中国石油化工股份有限公司 2018-09-21 CN disclosed
CN-106146706-B Cationic polymerization method 中国石油化工股份有限公司 2018-09-21 CN disclosed
CN-106146708-B Cationic polymerization method 中国石油化工股份有限公司 2018-08-17 CN disclosed
CN-105440231-B Preparation method of block copolymer and block copolymer 中国石油化工股份有限公司 2018-03-02 CN disclosed
CN-104558357-B Cationic polymerization method 中国石油化工股份有限公司 2018-02-13 CN disclosed
CN-104558344-B Cationic polymerization initiator system, application thereof and cationic polymerization method 中国石油化工股份有限公司 2017-02-15 CN disclosed
CN-104974291-B Cationic polymerization method 中国石油化工股份有限公司 2017-02-15 CN disclosed
CN-104558342-B Cationic polymerization method 中国石油化工股份有限公司 2017-02-01 CN disclosed
CN-104558341-B Cationic polymerization initiator system, application thereof and cationic polymerization method 中国石油化工股份有限公司 2017-02-01 CN disclosed
CN-104558343-B Cationic polymerization method 中国石油化工股份有限公司 2017-01-25 CN disclosed
CN-104974290-B Cationic polymerization method 中国石油化工股份有限公司 2017-01-25 CN disclosed
CN-104974292-B Cationic polymerization method 中国石油化工股份有限公司 2017-01-25 CN disclosed
CN-1761672-A Thienopyrimidinediones and their use in modulating autoimmune diseases ASTRAZENECA AB (SE) 2006-04-19 CN disclosed