Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.78 |
| ▸ | ESR1 | P03372 | 8/20 | 0.78 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.78 |
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.61 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | ESRRB | O95718 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795604 | 1.00 | CYP19A1 (0.78) | CYP19A1ESR1ESR2LMNAMAPK1 | |
| SCHEMBL6346289 | 1.00 | CYP19A1 (0.78) | CYP19A1ESR1ESR2LMNAMAPK1 | |
| SCHEMBL2846408 | 1.00 | CYP19A1 (0.78) | CYP19A1ESR1ESR2LMNAMAPK1 | |
| SCHEMBL12544534 | 1.00 | CYP19A1 (0.78) | CYP19A1ESR1ESR2LMNAMAPK1 | |
| SCHEMBL6346280 | 1.00 | CYP19A1 (0.78) | CYP19A1ESR1ESR2LMNAMAPK1 | |
| SCHEMBL2842300 | 1.00 | CYP19A1 (0.78) | CYP19A1ESR1ESR2LMNAMAPK1 | |
| SCHEMBL796194 | 1.00 | CYP19A1 (0.78) | CYP19A1ESR1ESR2LMNAMAPK1 | |
| SCHEMBL795609 | 1.00 | CYP19A1 (0.78) | CYP19A1ESR1ESR2LMNAMAPK1 | |
| SCHEMBL16480227 | 0.91 | CYP19A1 (0.78) | CYP19A1ESR1ESR2LMNAMAPK1 | |
| SCHEMBL14190685 | 0.88 | CYP19A1 (0.62) | CYP19A1ESR1ESR2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106255501-A | 6-substituted estradiol derivatives for the treatment of alzheimer's disease | 恩德切有限责任公司 | 2016-12-21 | — | — | CN | disclosed |