Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28116136 | 0.95 | NAMPT (0.77) | NAMPTALDH1A1MAPTLMNAGAA | |
| SCHEMBL28116140 | 0.95 | NAMPT (0.80) | NAMPTALDH1A1MAPTLMNAGAA | |
| SCHEMBL28837244 | 0.93 | NAMPT (0.73) | NAMPTALDH1A1MAPTLMNAGAA | |
| SCHEMBL28116167 | 0.92 | NAMPT (0.72) | NAMPTALDH1A1MAPTLMNAGAA | |
| SCHEMBL28116519 | 0.92 | NAMPT (0.72) | NAMPTALDH1A1MAPTLMNAGAA | |
| SCHEMBL28116158 | 0.92 | NAMPT (0.72) | NAMPTALDH1A1MAPTLMNAGAA | |
| SCHEMBL28116253 | 0.92 | NAMPT (0.72) | NAMPTALDH1A1MAPTLMNAGAA | |
| SCHEMBL28116521 | 0.91 | NAMPT (0.69) | NAMPTALDH1A1MAPTLMNAGAA | |
| SCHEMBL28896021 | 0.90 | NAMPT (0.70) | NAMPTALDH1A1MAPTLMNAGAA | |
| SCHEMBL28116512 | 0.90 | NAMPT (0.70) | NAMPTALDH1A1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103709096-B | Urea type derivative used as nicotinamide ribose phosphate transferase inhibitor, as well as preparation method and application thereof | 中国人民解放军第二军医大学 | 2017-01-18 | — | — | CN | claimed |
| CN-103709096-B | Urea type derivative used as nicotinamide ribose phosphate transferase inhibitor, as well as preparation method and application thereof | 中国人民解放军第二军医大学 | 2017-01-18 | — | — | CN | disclosed |