SCHEMBL28116695

SCHEMBL28116695

Fc1ccccc1-c1cc(-c2ccccc2F)cc(-c2ccccc2F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.54
PTPN1 P18031 1/20 0.54
ACMSD Q8TDX5 1/20 0.47
BACE1 P56817 1/20 0.46
TRPA1 O75762 1/20 0.46
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
PDK2 Q15119 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.44
NPC1 O15118 2/20 0.43
ERN1 O75460 1/20 0.43
MAP4K4 O95819 1/20 0.43
TNKS O95271 1/20 0.42
TNKS2 Q9H2K2 1/20 0.42
ALOX5AP P20292 1/20 0.42
FEN1 P39748 1/20 0.42
MEN1 O00255 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28102163 0.90 PTPRC (0.47) PTPRCPTPN1ACMSDBACE1TRPA1
SCHEMBL12856837 0.89 PTPRC (0.55) PTPRCPTPN1ACMSDBACE1TRPA1
SCHEMBL29628986 0.89 PTPRC (0.55) PTPRCPTPN1ACMSDBACE1TRPA1
SCHEMBL20593949 0.88 PTPRC (0.46) PTPRCPTPN1ACMSDBACE1TRPA1
SCHEMBL30525628 0.87 PTPRC (0.48) PTPRCPTPN1ACMSDBACE1TRPA1
SCHEMBL13439489 0.87 PTPRC (0.48) PTPRCPTPN1ACMSDBACE1TRPA1
SCHEMBL18627028 0.87 PTPRC (0.48) PTPRCPTPN1ACMSDBACE1TRPA1
SCHEMBL12856709 0.87 PTPRC (0.53) PTPRCPTPN1ACMSDBACE1TRPA1
SCHEMBL30665737 0.87 PTPRC (0.48) PTPRCPTPN1ACMSDBACE1TRPA1
SCHEMBL12856701 0.85 PTPRC (0.56) PTPRCPTPN1ACMSDBACE1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217324-B Preparation method of 1,3, 5-trisubstituted benzene compound 中国科学院化学研究所 2025-03-18 CN claimed
CN-116217324-A Preparation method of 1,3, 5-trisubstituted benzene compound 中国科学院化学研究所 2023-06-06 CN claimed
CN-116217324-B Preparation method of 1,3, 5-trisubstituted benzene compound 中国科学院化学研究所 2025-03-18 CN disclosed
CN-116217324-A Preparation method of 1,3, 5-trisubstituted benzene compound 中国科学院化学研究所 2023-06-06 CN disclosed
CN-106366084-A Three-fold symmetrical triaza nano-graphite molecule and preparation method thereof 陕西理工大学 2017-02-01 CN disclosed
CN-106366084-A Three-fold symmetrical triaza nano-graphite molecule and preparation method thereof 陕西理工大学 2017-02-01 CN disclosed