Isophthalic Acid

Isophthalic Acid

SCHEMBL28117578

C=CCOC(=O)c1ccccc1C(=O)OCC=C.O=C(O)c1cccc(C(=O)O)c1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.73
ALDH1A1 P00352 2/20 0.59
TSHR P16473 2/20 0.59
HSD17B10 Q99714 1/20 0.59
FFAR1 O14842 1/20 0.45
NPC1 O15118 2/20 0.44
KDM4E B2RXH2 2/20 0.44
RAB9A P51151 1/20 0.44
AKR1C3 P42330 1/20 0.42
RHOA P61586 1/20 0.42
KMO O15229 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NR4A2 P43354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11157978 0.91 CYP3A4 (0.77) CYP3A4ALDH1A1TSHRHSD17B10NPC1
SCHEMBL2392472 0.89 CYP3A4 (0.54) CYP3A4ALDH1A1TSHRHSD17B10FFAR1
Terephthalic Acid SCHEMBL27490081 0.89 CYP3A4 (0.80) CYP3A4ALDH1A1TSHRHSD17B10NPC1
SCHEMBL28870175 0.88 CYP3A4 (0.69) CYP3A4ALDH1A1TSHRHSD17B10FFAR1
Phthalic Acid SCHEMBL15689679 0.88 CYP3A4 (0.63) CYP3A4ALDH1A1TSHRHSD17B10NPC1
Phosphine SCHEMBL10982972 0.88 CYP3A4 (0.53) CYP3A4ALDH1A1TSHRHSD17B10FFAR1
Isophthalic Acid SCHEMBL28712224 0.88 CYP3A4 (0.53) CYP3A4ALDH1A1TSHRHSD17B10FFAR1
Phthalic Acid SCHEMBL23929049 0.85 CYP3A4 (0.86) CYP3A4ALDH1A1TSHRHSD17B10NPC1
Benzene SCHEMBL7689916 0.85 CYP3A4 (0.86) CYP3A4ALDH1A1TSHRHSD17B10NPC1
SCHEMBL87635 0.85 CYP3A4 (0.86) CYP3A4ALDH1A1TSHRHSD17B10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106243945-A A kind of polish lacquer being sprayed on racket 安徽翰文运动用品股份有限公司 2016-12-21 CN disclosed