Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.76 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.68 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.67 |
| ▸ | RET | P07949 | 1/20 | 0.67 |
| ▸ | MET | P08581 | 1/20 | 0.67 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.67 |
| ▸ | TEC | P42680 | 1/20 | 0.67 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.67 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.67 |
| ▸ | BTK | Q06187 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.67 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9883218 | 0.88 | EGFR (0.84) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL3423119 | 0.88 | EGFR (0.88) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL28117293 | 0.88 | EGFR (0.77) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL5207429 | 0.88 | EGFR (0.85) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL28117875 | 0.88 | EGFR (0.76) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL3395768 | 0.86 | EGFR (0.89) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL3391925 | 0.86 | EGFR (1.00) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL3423001 | 0.86 | EGFR (0.78) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL3695693 | 0.86 | EGFR (0.78) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL3391495 | 0.86 | EGFR (0.78) | EGFRERBB2RIPK2RETMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279128-B | Epoxyethane derivative and preparation method thereof and application in medicine | 四川海思科制药有限公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-106279128-A | Epoxyethane derivative and preparation method thereof and in application pharmaceutically | 四川海思科制药有限公司 | 2017-01-04 | — | — | CN | disclosed |