SCHEMBL28117976

SCHEMBL28117976

O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(CCc2cccs2)c1

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SNCA P37840 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15313095 0.93 SNCA (1.00) SNCA
SCHEMBL28118362 0.91 SNCA (0.86) SNCA
SCHEMBL9937713 0.90 SNCA (1.00) SNCA
SCHEMBL9938101 0.85 SNCA (1.00) SNCA
SCHEMBL9938016 0.85 SNCA (0.83) SNCA
SCHEMBL15313159 0.84 SNCA (1.00) SNCA
SCHEMBL9938959 0.83 SNCA (1.00) SNCA
SCHEMBL9938450 0.83 SNCA (1.00) SNCA
SCHEMBL15313136 0.83 SNCA (1.00) SNCA
SCHEMBL15313105 0.82 SNCA (1.00) SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103261156-B For treating the noval chemical compound of neurodegenerative disease 鲁汶天主教大学研究开发部 2016-12-28 CN disclosed