Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27261131 | 0.81 | TP53 (0.48) | MAPTMEN1KMT2AMAPK1CASP1 | |
| SCHEMBL14996608 | 0.80 | MAPT (0.47) | MAPTMEN1KMT2AMAPK1CASP1 | |
| SCHEMBL10337766 | 0.80 | MAPT (0.51) | MAPTMEN1KMT2AMAPK1CASP1 | |
| SCHEMBL4214390 | 0.77 | MAPT (0.58) | MAPTMEN1KMT2AMAPK1CASP1 | |
| SCHEMBL266137 | 0.77 | RECQL (0.58) | MAPTMEN1KMT2AMAPK1CASP1 | |
| SCHEMBL17290611 | 0.77 | RECQL (0.46) | MAPTMEN1KMT2AMAPK1CASP1 | |
| SCHEMBL12731851 | 0.77 | MEN1 (0.41) | MAPTMEN1KMT2AMAPK1CASP1 | |
| SCHEMBL12806568 | 0.77 | SMN1; SMN2 (0.48) | MAPTMEN1KMT2AMAPK1CASP1 | |
| SCHEMBL12859402 | 0.74 | MAPT (0.42) | MAPTMEN1KMT2AMAPK1CASP1 | |
| SCHEMBL10960207 | 0.73 | KDM4E (0.49) | MEN1KMT2ARECQLBRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397377-B | The method of fluorine on a kind of electron rich five-ring heterocycles acid and its derivative decarboxylation | 中南大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-106397377-A | Electron-rich five-membered heterocyclic acid and method for decarboxylation and fluorination of derivative thereof | 中南大学 | 2017-02-15 | — | — | CN | disclosed |