SCHEMBL28118410

SCHEMBL28118410

N#Cc1cccc(Cc2ccc(C(=O)N=[N+]=NCCc3c[nH]c4ccc(Cl)cc34)cc2)c1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SNCA P37840 19/20 0.68
MAPT P10636 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28118355 0.94 SNCA (0.68) SNCAMAPT
SCHEMBL28118091 0.93 SNCA (0.67) SNCAMAPT
SCHEMBL28952739 0.92 SNCA (0.66) SNCAMAPT
SCHEMBL28837746 0.92 SNCA (0.68) SNCA
SCHEMBL28117865 0.88 SNCA (0.66) SNCA
SCHEMBL28118357 0.86 SNCA (0.68) SNCAMAPT
SCHEMBL28118405 0.85 SNCA (0.65) SNCA
SCHEMBL28117986 0.84 SNCA (0.64) SNCA
SCHEMBL28837731 0.84 SNCA (0.67) SNCA
SCHEMBL28117999 0.83 SNCA (0.69) SNCAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103261156-B For treating the noval chemical compound of neurodegenerative disease 鲁汶天主教大学研究开发部 2016-12-28 CN disclosed