1,2-Dimethoxybenzene

1,2-Dimethoxybenzene

SCHEMBL28118612

COc1ccccc1OC.NC(N)=O

nearest known ligand 0.72

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.72
CA2 P00918 3/20 0.72
CA12 O43570 2/20 0.72
CA7 P43166 2/20 0.72
CA9 Q16790 2/20 0.72
CA14 Q9ULX7 2/20 0.72
CA4 P22748 1/20 0.72
SMN1; SMN2 Q16637 2/20 0.59
POLB P06746 1/20 0.59
HTT P42858 3/20 0.57
CTSD P07339 1/20 0.57
KMT2A Q03164 1/20 0.57
ALDH1A1 P00352 4/20 0.56
TP53 P04637 1/20 0.56
TSHR P16473 1/20 0.56
ADRA2B P18089 1/20 0.56
PTGS1 P23219 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
LMNA P02545 2/20 0.55
MAPK1 P28482 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dimethoxybenzene SCHEMBL27679751 0.89 CA1 (0.72) CA1CA2CA12CA7CA9
1,2-Dimethoxybenzene SCHEMBL27898360 0.89 CA1 (0.72) CA1CA2CA12CA7CA9
1,2-Dimethoxybenzene SCHEMBL27470563 0.86 CA1 (0.68) CA1CA2CA12CA7CA9
SCHEMBL3952526 0.85 CA1 (0.59) CA1CA2CA12CA7CA9
1,2-Dimethoxybenzene SCHEMBL27891985 0.85 CA1 (0.87) CA1CA2CA12CA7CA9
1,2-Dimethoxybenzene SCHEMBL27422983 0.85 CA1 (0.87) CA1CA2CA12CA7CA9
1,2-Dimethoxybenzene SCHEMBL29351917 0.85 CA1 (1.00) CA1CA2CA12CA7CA9
1,2-Dimethoxybenzene SCHEMBL5308636 0.85 CA1 (1.00) CA1CA2CA12CA7CA9
1,2-Dimethoxybenzene SCHEMBL105872 0.85 CA1 (1.00) CA1CA2CA12CA7CA9
1,2-Dimethoxybenzene SCHEMBL27751216 0.84 CA1 (0.65) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232667-A Poly-isourea 巴斯夫欧洲公司 2016-12-14 CN disclosed