Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2719155 | 0.80 | — | — | |
| SCHEMBL9715421 | 0.68 | TSHR (0.62) | TSHRLMNATHRBPMP22HSD17B10 | |
| Sulfuric Acid SCHEMBL28316076 | 0.68 | TSHR (0.60) | TSHRLMNATHRBPMP22HSD17B10 | |
| SCHEMBL31091056 | 0.65 | — | — | |
| SCHEMBL937506 | 0.65 | TSHR (0.55) | TSHRLMNATHRBPMP22HSD17B10 | |
| Sulfamate SCHEMBL16687154 | 0.65 | TSHR (0.55) | TSHRLMNATHRBPMP22HSD17B10 | |
| Hydrogen Peroxide SCHEMBL298462 | 0.63 | TSHR (0.87) | TSHR | |
| Hydrogen Peroxide SCHEMBL30110573 | 0.63 | TSHR (0.87) | TSHR | |
| SCHEMBL385555 | 0.63 | TSHR (1.00) | TSHR | |
| SCHEMBL11606739 | 0.63 | TSHR (1.00) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565742-A | Indolone screw tetralin sulfo-pyran derivative and preparing method and application thereof | 中国人民解放军第四军医大学 | 2017-04-19 | — | — | CN | disclosed |
| CN-106565742-A | Indolone screw tetralin sulfo-pyran derivative and preparing method and application thereof | 中国人民解放军第四军医大学 | 2017-04-19 | — | — | CN | disclosed |