SCHEMBL28118799

SCHEMBL28118799

O=P(O)(O)CCCCP(=O)(O)OCO

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.50
LPAR3 Q9UBY5 3/20 0.44
LPAR2 Q9HBW0 1/20 0.44
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
NFKB1 P19838 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
PPARD Q03181 1/20 0.41
BBOX1 O75936 2/20 0.38
CETP P11597 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15438059 0.79 PPARD (0.61) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL28252207 0.77 CAMK2A (0.42) LMNANFKB1BLMPMP22PPARD
SCHEMBL20235 0.76 TYMS (0.85) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL28058181 0.74 PPARD (0.40) LMNABLMPPARDCETP
SCHEMBL28798283 0.73 TYMS (0.52) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL12112826 0.73 TYMS (0.52) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL28639884 0.73 TYMS (0.52) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL20917634 0.73 LPAR3 (0.69) LPAR3LPAR2PPARDCETP
SCHEMBL767546 0.73 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL630093 0.73 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106414747-A Cytokinin synthase, constructs, and related methods 美国陶氏益农公司 2017-02-15 CN claimed
CN-106414747-A Cytokinin synthase, constructs, and related methods 美国陶氏益农公司 2017-02-15 CN disclosed