SCHEMBL28118822

SCHEMBL28118822

NC(=O)NC(=O)NC1=CC=CC1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.50
POLB P06746 1/20 0.42
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
CRBN Q96SW2 1/20 0.32
DRD2 P14416 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7653028 0.84
SCHEMBL19312242 0.77 EPHX2 (0.41) EPHX2ALDH1A1
SCHEMBL27898077 0.72
SCHEMBL10219073 0.72 EPHX2 (0.44) EPHX2POLB
SCHEMBL10219055 0.69 EPHX2 (0.45) EPHX2POLBALDH1A1
SCHEMBL12247919 0.69 EPHX2 (0.45) EPHX2
SCHEMBL25607905 0.69 EPHX2 (0.45) EPHX2ALDH1A1
SCHEMBL19353235 0.68 EPHX2 (0.44) EPHX2
SCHEMBL12599199 0.68 EPHX2 (0.44) EPHX2POLB
SCHEMBL28921826 0.67 EPHX2 (0.47) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-205844250-U A kind of chiral sensor based on graphene field effect transistor 无锡盈芯半导体科技有限公司 2016-12-28 CN disclosed