Methylamine

Methylamine

SCHEMBL28118971

CCCCCCc1ccccc1.CN

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.67
HTR2A P28223 2/20 0.63
SIGMAR1 Q99720 5/20 0.58
MAOA P21397 1/20 0.58
ESR1 P03372 2/20 0.57
ADRA2A P08913 2/20 0.57
ADORA3 P0DMS8 2/20 0.57
TACR2 P21452 2/20 0.57
SLC6A2 P23975 2/20 0.57
SLC6A4 P31645 2/20 0.57
SLC6A3 Q01959 2/20 0.57
KDM4E B2RXH2 1/20 0.57
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
SHBG P04278 1/20 0.57
TP53 P04637 1/20 0.57
CYP3A4 P08684 1/20 0.57
HSPD1 P10809 1/20 0.57
ADRB3 P13945 1/20 0.57
HTR2C P28335 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL27692859 1.00 KCNH2 (0.67) KCNH2HTR2ASIGMAR1MAOAESR1
Methylamine SCHEMBL27596716 1.00 KCNH2 (0.67) KCNH2HTR2ASIGMAR1MAOAESR1
Methylamine SCHEMBL27712583 1.00 KCNH2 (0.67) KCNH2HTR2ASIGMAR1MAOAESR1
Methylamine SCHEMBL6014456 0.98 KCNH2 (0.63) KCNH2HTR2ASIGMAR1MAOAESR1
Decane SCHEMBL8740719 0.95 KCNH2 (0.71) KCNH2HTR2ASIGMAR1MAOAESR1
SCHEMBL175633 0.95 KCNH2 (0.71) KCNH2HTR2ASIGMAR1MAOAESR1
SCHEMBL10995503 0.95 KCNH2 (0.71) KCNH2HTR2ASIGMAR1MAOAESR1
SCHEMBL210629 0.95 KCNH2 (0.71) KCNH2HTR2ASIGMAR1MAOAESR1
SCHEMBL4465463 0.95 KCNH2 (0.71) KCNH2HTR2ASIGMAR1MAOAESR1
SCHEMBL11231313 0.95 KCNH2 (0.71) KCNH2HTR2ASIGMAR1MAOAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106397217-A Method for synthesizing dextral alpha-cyclohexylbenzylamine 王际菊 2017-02-15 CN disclosed