SCHEMBL28123545

SCHEMBL28123545

C[C@@H](O)CCc1ccc2c(c1)OCO2

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.57
SLC6A4 P31645 3/20 0.57
SLC6A2 P23975 2/20 0.57
SLC6A3 Q01959 2/20 0.57
CYP3A4 P08684 3/20 0.55
CALM1 P0DP23 3/20 0.54
CYP2D6 P10635 2/20 0.54
NPSR1 Q6W5P4 1/20 0.52
HPGD P15428 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC8 Q9BY41 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29664514 1.00 TAAR1 (0.57) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL2485767 1.00 TAAR1 (0.57) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL10783476 0.91 TAAR1 (0.50) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL8294114 0.86 TAAR1 (0.61) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL987525 0.83 TAAR1 (0.71) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL4168488 0.83 TAAR1 (0.70) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL4168491 0.83 TAAR1 (0.70) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL4170645 0.83 TAAR1 (0.70) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL30147114 0.83 TAAR1 (0.70) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL11389818 0.81 TAAR1 (0.48) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106478588-A A kind of chiral 1 piperonyl 2 propanol and its isomery preparation 王际菊 2017-03-08 CN claimed
CN-106478588-A A kind of chiral 1 piperonyl 2 propanol and its isomery preparation 王际菊 2017-03-08 CN disclosed