Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820790 | 0.92 | POLB (0.63) | POLBGAATSHRIMPDH2IMPDH1 | |
| SCHEMBL104280 | 0.90 | POLB (0.66) | POLBGAATSHRIMPDH2IMPDH1 | |
| SCHEMBL29518610 | 0.90 | POLB (0.66) | POLBGAATSHRIMPDH2IMPDH1 | |
| SCHEMBL28008968 | 0.88 | POLB (0.63) | POLBGAATSHRIMPDH2IMPDH1 | |
| Hydrochloric Acid SCHEMBL1144931 | 0.88 | POLB (0.63) | POLBGAATSHRIMPDH2IMPDH1 | |
| Anisole SCHEMBL28131523 | 0.85 | POLB (0.71) | POLBGAAIMPDH2IMPDH1AR | |
| SCHEMBL20512354 | 0.83 | CYP2A6 (0.59) | POLBGAATSHRIMPDH2IMPDH1 | |
| Ethylene Glycol SCHEMBL28971846 | 0.81 | GAA (0.56) | POLBGAATSHRIMPDH2IMPDH1 | |
| SCHEMBL28994453 | 0.81 | TSHR (0.69) | POLBGAATSHRIMPDH2IMPDH1 | |
| Ammonia Solution, Strong SCHEMBL3942484 | 0.81 | POLB (0.56) | POLBGAATSHRIMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278841-B | A kind of preparation method of 8- methoxyl groups -3,4- dihydro -1H-2- naphthalenones | 浙江永太药业有限公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-106278841-B | A kind of preparation method of 8- methoxyl groups -3,4- dihydro -1H-2- naphthalenones | 浙江永太药业有限公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-106278841-A | A kind of preparation method of 8 methoxyl group 3,4 dihydro 1H 2 naphthalenones | 浙江永太药业有限公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-106278841-A | A kind of preparation method of 8 methoxyl group 3,4 dihydro 1H 2 naphthalenones | 浙江永太药业有限公司 | 2017-01-04 | — | — | CN | disclosed |