Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1588660 | 0.82 | HRH4 (0.66) | HRH4 | |
| SCHEMBL1588643 | 0.82 | HRH4 (0.66) | HRH4 | |
| SCHEMBL19233347 | 0.82 | HRH4 (0.66) | HRH4 | |
| SCHEMBL19233409 | 0.82 | HRH4 (0.76) | HRH4 | |
| SCHEMBL15721552 | 0.82 | HRH4 (0.66) | HRH4 | |
| SCHEMBL1589070 | 0.80 | HRH4 (0.90) | HRH4 | |
| SCHEMBL12702844 | 0.80 | HRH4 (0.90) | HRH4 | |
| Hydrochloric Acid SCHEMBL846070 | 0.78 | HRH4 (0.88) | HRH4 | |
| SCHEMBL28124944 | 0.78 | HRH4 (0.63) | HRH4 | |
| SCHEMBL28125394 | 0.78 | HRH4 (0.63) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102118969-B | Diaminopyridine, diaminopyrimidine and diaminopyridazine modulators of the histamine H4 receptor | 詹森药业有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-102118969-B | Diaminopyridine, diaminopyrimidine and diaminopyridazine modulators of the histamine H4 receptor | 詹森药业有限公司 | 2017-03-08 | — | — | CN | disclosed |