Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038665 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2CA2KMT2AHDAC3HDAC1 | |
| SCHEMBL12832761 | 0.84 | SMN1; SMN2 (0.81) | SMN1; SMN2CA2HDAC3HDAC1NPC1 | |
| SCHEMBL3030613 | 0.83 | MAOB (0.62) | SMN1; SMN2CYP1A2TSHRNFKB1MAOB | |
| SCHEMBL28984149 | 0.83 | SMN1; SMN2 (0.84) | SMN1; SMN2CA2HDAC3HDAC1NPC1 | |
| SCHEMBL10064731 | 0.83 | SMN1; SMN2 (0.84) | SMN1; SMN2CA2HDAC3HDAC1NPC1 | |
| SCHEMBL1416416 | 0.83 | HPGD (0.56) | SMN1; SMN2KMT2AMEN1NPC1HPGD | |
| SCHEMBL29230045 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2CA2CYP1A2TSHRNFKB1 | |
| SCHEMBL29104753 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2CA2CYP1A2TSHRNFKB1 | |
| SCHEMBL23568255 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2CA2CYP1A2TSHRNFKB1 | |
| SCHEMBL23569027 | 0.81 | KMT2A (0.68) | SMN1; SMN2CA2KMT2AMEN1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459089-A | Biotin variants, streptavidin mutants and uses thereof | 赛威德医疗公司 | 2017-02-22 | — | — | CN | disclosed |