Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.76 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.76 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815844 | 1.00 | ABCB1 (0.76) | ABCB1ABCG2PDE4BMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2812613 | 0.99 | ABCB1 (0.75) | ABCB1ABCG2PDE4BMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2812617 | 0.99 | ABCB1 (0.75) | ABCB1ABCG2PDE4BMAPTALDH1A1 | |
| SCHEMBL2816397 | 0.97 | ABCB1 (0.72) | ABCB1ABCG2PDE4BMAPTALDH1A1 | |
| SCHEMBL2816395 | 0.97 | ABCB1 (0.72) | ABCB1ABCG2PDE4BMAPTALDH1A1 | |
| SCHEMBL2814572 | 0.94 | ABCB1 (0.68) | ABCB1ABCG2PDE4BMAPTALDH1A1 | |
| SCHEMBL2817818 | 0.94 | ABCB1 (0.68) | ABCB1ABCG2PDE4BMAPTALDH1A1 | |
| SCHEMBL2814569 | 0.94 | ABCB1 (0.68) | ABCB1ABCG2PDE4BMAPTALDH1A1 | |
| SCHEMBL2817822 | 0.94 | ABCB1 (0.68) | ABCB1ABCG2PDE4BMAPTALDH1A1 | |
| SCHEMBL2814642 | 0.93 | ABCB1 (0.67) | ABCB1ABCG2PDE4BMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249089-A1 | ABCG2 INHIBITOR | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2010-09-30 | — | — | US | claimed |
| EP-2218719-A1 | ABCG2 INHIBITOR | Kabushiki Kaisha Yakult Honsha (JP) | 2010-08-18 | — | — | EP | claimed |
| US-20100249089-A1 | ABCG2 INHIBITOR | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2218719-A1 | ABCG2 INHIBITOR | Kabushiki Kaisha Yakult Honsha (JP) | 2010-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249089-A1 | ABCG2 INHIBITOR | ABCC1, ABCB1, ABCC5 | ABCB1 2/4885ABCG2 7/4885PDE4B 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.