Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | CES2 | O00748 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.59 |
| ▸ | IDO1 | P14902 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28841602 | 0.89 | MEN1 (0.63) | MEN1ALDH1A1KMT2ACES2HPGD | |
| SCHEMBL28128127 | 0.86 | MEN1 (0.55) | MEN1ALDH1A1KMT2ACES2HPGD | |
| SCHEMBL28135613 | 0.86 | MEN1 (0.55) | MEN1ALDH1A1KMT2ACES2HPGD | |
| Tanshinone Iia Sulfonic Acid SCHEMBL14417738 | 0.78 | MEN1 (0.80) | MEN1ALDH1A1KMT2ACES2HPGD | |
| SCHEMBL14417726 | 0.75 | MEN1 (0.64) | MEN1ALDH1A1KMT2ACES2HPGD | |
| SCHEMBL28411969 | 0.74 | MEN1 (0.67) | MEN1ALDH1A1KMT2ACES2HPGD | |
| SCHEMBL14417741 | 0.74 | MEN1 (0.67) | MEN1ALDH1A1KMT2ACES2HPGD | |
| SCHEMBL14417881 | 0.74 | MEN1 (0.80) | MEN1ALDH1A1KMT2ACES2HPGD | |
| Tanshinone Iia Sulfonic Acid SCHEMBL28665868 | 0.74 | MEN1 (1.00) | MEN1ALDH1A1KMT2ACES2HPGD | |
| Tanshinone Iia Sulfonic Acid SCHEMBL30094475 | 0.74 | MEN1 (1.00) | MEN1ALDH1A1KMT2ACES2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478765-A | Tanshinone ⅡA sulfonic acid and its synthesis and the application as medicine | 陈剑 | 2017-03-08 | — | — | CN | claimed |