Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14868318 | 1.00 | SCN5A (0.48) | SCN5ASCN2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14868324 | 0.91 | SCN5A (0.55) | SCN5ASCN2ANPC1RAB9ASMN1; SMN2 | |
| Nitric Acid SCHEMBL11800507 | 0.91 | SCN5A (0.45) | SCN5ASCN2ANPC1RAB9ASMN1; SMN2 | |
| Nitric Acid SCHEMBL11800504 | 0.91 | SCN5A (0.45) | SCN5ASCN2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14868322 | 0.84 | GRIN2D (0.46) | SCN5ASCN2ASMN1; SMN2GAAIDO1 | |
| SCHEMBL14208732 | 0.84 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2LMNATAAR1 | |
| SCHEMBL14208752 | 0.84 | GRIN1 (0.47) | SCN5ASCN2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14208814 | 0.84 | GRIN2B (0.47) | NPC1RAB9ASMN1; SMN2LMNATAAR1 | |
| SCHEMBL13684805 | 0.84 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2LMNATAAR1 | |
| SCHEMBL13684857 | 0.84 | GRIN2B (0.47) | NPC1RAB9ASMN1; SMN2LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458868-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-111848494-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-111848494-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-106458868-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2017-02-22 | — | — | CN | disclosed |