Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2812901 | 1.00 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL2811950 | 0.90 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL2810955 | 0.90 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL2810961 | 0.90 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL2811952 | 0.90 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL2808853 | 0.89 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL2808858 | 0.89 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL2813283 | 0.87 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL2813279 | 0.87 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL2810887 | 0.87 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278473-B2 | Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-02 | — | — | US | disclosed |
| US-20100240729-A1 | ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-23 | — | — | US | disclosed |
| WO-2009064031-A1 | ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240729-A1 | ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME | OXER1, CBR1, DEGS1 | NPC1 3668/4885RAB9A 1842/4885SMN1; SMN2 1135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.