Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324666 | 0.90 | RECQL (0.58) | RECQLHDAC1HDAC2PDE4BPOLB | |
| SCHEMBL5610571 | 0.85 | RECQL (0.61) | RECQLHDAC1HDAC2PDE4BPOLB | |
| SCHEMBL134754 | 0.84 | RECQL (0.67) | RECQLHDAC1HDAC2PDE4BPOLB | |
| SCHEMBL4860600 | 0.82 | KDM4E (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21255817 | 0.82 | KDM4E (0.66) | RECQLHDAC1HDAC2PDE4BKDM4E | |
| SCHEMBL9506664 | 0.81 | KDM4E (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7184663 | 0.81 | KDM4E (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2802611 | 0.81 | KDM4E (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL7355268 | 0.81 | KDM4E (0.64) | RECQLHDAC1HDAC2PDE4BKDM4E | |
| SCHEMBL7333965 | 0.81 | PDE4B (0.56) | RECQLPDE4BMEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565743-B | One kind is containing tetrahydroisoquinoline and carbamate compound and its preparation method and application | 华南农业大学 | 2018-06-19 | — | — | CN | disclosed |
| CN-106565743-A | Tetrahydroisoquinoline and carbamate containing compound, preparation method therefor and application of compound | 华南农业大学 | 2017-04-19 | — | — | CN | disclosed |