Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butadiene SCHEMBL7152775 | 0.84 | MAPT (0.41) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL9014947 | 0.81 | MAPT (0.39) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL28239388 | 0.80 | MAPT (0.35) | MAPTGAATSHRALDH1A1LMNA | |
| Ethylene SCHEMBL9551923 | 0.79 | MAPT (0.47) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL29398195 | 0.79 | — | — | |
| SCHEMBL3767165 | 0.79 | MAPT (0.53) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL29418986 | 0.79 | MAPT (0.53) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL33554 | 0.79 | — | — | |
| SCHEMBL29375766 | 0.79 | MAPT (0.53) | MAPTGAATSHRALDH1A1LMNA | |
| SCHEMBL27566643 | 0.79 | MAPT (0.53) | MAPTGAATSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748997-B | Addition polymers from monomers containing nitrogen heterocycles and monomers containing vinyl aryl cyclobutenes | 罗门哈斯电子材料有限责任公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-106543002-A | Arylcyclobutene | 陶氏环球技术有限责任公司 | 2017-03-29 | — | — | CN | disclosed |