Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709764 | 0.75 | CYP1A2 (0.48) | AXLPLAUNOS1 | |
| SCHEMBL13765864 | 0.75 | CYP1A2 (0.48) | AXLPLAU | |
| SCHEMBL4068083 | 0.75 | AXL (0.55) | AXLPLAU | |
| SCHEMBL28135487 | 0.75 | CYP3A4 (0.42) | — | |
| SCHEMBL13724624 | 0.75 | PLAU (0.33) | AXLPLAUNOS1 | |
| SCHEMBL2190572 | 0.75 | CYP1A2 (0.48) | AXLPLAUNOS1 | |
| SCHEMBL7836754 | 0.75 | PARP1 (0.43) | AXLPLAUNOS1PRNP | |
| SCHEMBL29191973 | 0.71 | AXL (0.36) | AXL | |
| SCHEMBL26108508 | 0.71 | KDM4E (0.39) | PLAU | |
| SCHEMBL4519096 | 0.68 | TDP1 (0.57) | NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447547-B | Synthesis method of 4-aminoisoquinoline-8-methyl formate | 苏州康润医药有限公司 | 2017-04-19 | — | — | CN | claimed |
| CN-104447547-B | Synthesis method of 4-aminoisoquinoline-8-methyl formate | 苏州康润医药有限公司 | 2017-04-19 | — | — | CN | disclosed |