Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 15/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 9/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 8/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383089 | 0.93 | TYMP (0.36) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL13134622 | 0.93 | TYMP (0.36) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL13134620 | 0.93 | TYMP (0.36) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL13134609 | 0.82 | TYMP (0.35) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL383115 | 0.81 | TYMP (0.38) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL13130124 | 0.77 | P2RY6 (0.35) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL13765505 | 0.77 | P2RY6 (0.35) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL13134584 | 0.77 | P2RY6 (0.35) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL13134623 | 0.77 | TYMP (0.34) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL13134608 | 0.77 | TYMP (0.34) | P2RY6P2RY2P2RY4P2RY14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249068-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249068-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | PNP, TYMP, NTPCR | P2RY6 93/4885P2RY2 103/4885P2RY4 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.