Phthalic Acid

Phthalic Acid

SCHEMBL28140752

CCCCOP(=O)(O)OCc1ccccc1.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.59
CETP P11597 4/20 0.58
ALDH1A1 P00352 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
CYP3A4 P08684 1/20 0.53
MAPK1 P28482 1/20 0.53
PLK1 P53350 2/20 0.47
LTB4R2 Q9NPC1 1/20 0.45
PLA2G2D Q9UNK4 1/20 0.43
PTPN11 Q06124 1/20 0.43
PLK3 Q9H4B4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2914825 0.92 TSHR (0.71) TSHRCETPALDH1A1TDP1L3MBTL1
SCHEMBL11773273 0.87 TSHR (0.69) TSHRCETPALDH1A1TDP1L3MBTL1
Phthalic Acid SCHEMBL28643491 0.86 PTPN11 (0.56) TSHRCETPALDH1A1CYP3A4MAPK1
SCHEMBL28176231 0.86 CETP (0.68) TSHRCETPPLA2G2D
SCHEMBL11149582 0.86 TSHR (0.62) TSHRCETPALDH1A1TDP1L3MBTL1
SCHEMBL28603370 0.86 CETP (0.68) TSHRCETPPLA2G2D
SCHEMBL10778039 0.86 CETP (0.68) TSHRCETPPLA2G2D
Ammonia Solution, Strong SCHEMBL27681493 0.85 CETP (0.67) TSHRCETPPLA2G2D
SCHEMBL11538055 0.82 TSHR (0.76) TSHRCETPALDH1A1TDP1L3MBTL1
SCHEMBL30310287 0.81 CETP (0.54) TSHRCETPL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104277143-B VINYL CHLORIDE RESIN AGGREGATE PARTICLE, METHOD FOR PRODUCING SAME, AND GLOVES COMPRISING SAME 株式会社钟化 2017-04-12 CN disclosed